Imunofan refers to medicines that stimulate immunity.
Form of issue and composition
The drug is available in the form of suppositories rectal, spray nasal dosed and solution for subcutaneous and intramuscular injection.
Suppositories rectal Imunofan for 5 pcs. are placed in contour squares, 1 package per carton.
Spray nasal dosed is realized in plastic bottles with a dispensing device, designed for 40 doses. Each bottle is placed in a cardboard box.
Solution for subcutaneous and intramuscular administration Imunofan is realized in ampoules of 1 ml. In the carton box there are 5 ampoules of the drug.
The active substance of Imunofan is imunofan (arginyl-alpha-aspartyl-lysyl-valyl-tyrosyl-arginine).
Suppositories for rectal administration of Imunofan contain: imunofan (100 μg) and excipients (solid fat, glycine, tween 80, purified water).
One dose of the nasal spray imunofan has in its composition: imunofan (50 μg) and auxiliary substances (glycine, benzalkonium chloride, Trilon B, sodium chloride, purified water).
The composition of the solution for IM and SC administration include: imunofan (50 μg) and excipients (sodium chloride, glycine, water for injection).
Indications for use
Imunofan is used in the complex therapy of immunodeficiency states. It is prescribed for the treatment of the following diseases:
- Herpes virus 1 and 2 types, toxoplasma, cytomegalovirus, chlamydia, cryptospores;
- Chronic hepatitis C and B;
- HIV infection and AIDS;
- Tumors that are caused by HPV;
- Rheumatoid arthritis;
- Bacterial endocarditis;
- Durable healing wounds, burns.
The drug Imunofan is used for the prevention and treatment of chronic and acute infectious and inflammatory diseases.
In adult patients, rectal suppositories and solution for IM and / or administration imunofan are used as an adjuvant for vaccination against viral and bacterial infections.
Contraindications to the use of Imunofan are such states:
- Individual hypersensitivity to the components of the drug;
- Child age is up to two years.
Dosing and Administration
The single and daily dosage of the solution for IM and SC administration is 50 μg. Daily and single dose of rectal suppositories - 1 suppository (100 μg).
When using the nasal spray of Imunofan, the vial is held vertically, upwards with a spray, then the protective cap is removed from the nebulizer. Before the first use it is necessary to fill the dosing pump. To do this, press 3-4 times on the wide rim of the sprayer. After this, the nebulizer is inserted into the nasal passage, the head is held vertically. Once press the wide rim of the spray gun until it stops. A single dose of the drug contains 50 μg of active substance. The daily dosage should not be more than 200 mcg.
Multiplicity of admission and duration of therapy depends on the disease and is:
- With oncological diseases as part of the combined radical treatment: once a day, 8-10 days (8-10 suppositories, injections or doses of spray) before the operation and chemoradiotherapy, followed by a repeat of the course throughout the treatment, taking breaks for 15-20 days;
- In case of common tumor processes, 3-4 stages of different localization in the form of symptomatic or complex treatment: once a day, 8-10 days (8-10 suppositories, injections or doses of spray), then take a break for 15-20 days and repeat therapy courses with interruptions during the entire period of therapy;
- In chronic and acute infectious and inflammatory diseases, which are accompanied by signs of immunodeficiency and intoxication: 1 dose of nasal spray Imunofan in each nasal passage twice a day, for 10-15 days;
- With herpetic and CMV infection, cryptosporidosis, pneumocystose, chlamydia, toxoplasmosis: solution for IM and / or administration and suppositories rectal - once a day, the course of therapy - 15-20 days; Spray nasal 1 dose twice a day, treatment course - 10-15 days. The courses are repeated after 2-4 weeks if necessary;
- With HIV infection: once a day, the course of therapy - 15-20 days, it is possible to repeat the course of treatment after a break of 2-4 weeks;
- With diphtheria: once a day, the course of therapy is 8-10 days. In the case of diphtheria bacteriocarrier - 1 time in three days, with a course of 3-5 suppositories (3-5 injections);
- With chronic brucellosis and chronic viral hepatitis: 1 time per day, the course of therapy 15-20 days. In order to prevent recurrence, repeat the course in 2-3 months, in case of using nasal spray - after 4-6 months;
- With psoriasis: once a day, the course of therapy - 15-20 days;
- With rheumatoid arthritis, cholecystopancreatitis, bronchial obstructive syndrome: 1 time in three days, treatment course - 8-10 suppositories or 8-10 injections. If necessary, it is possible to continue therapy to 20 suppositories or injections according to the same scheme;
- With burns of 3-4 degrees with septicotoxemia and toxemia, in surgical patients with purulent-septic complications, long unhealed wounds of the extremities, septic endocarditis: once a day, the course of therapy is 7-10 days, if necessary, therapy is continued up to 20 days.
Children are prescribed the following dosages of Imunofan:
- In malignant diseases of the lymphoid and hematopoietic systems: 1 time per day for 10-20 days. The drug is prescribed throughout the course of chemoradiotherapy, as well as after its completion in order to prevent the development of toxicosis;
- With papillomatosis oropharynx and larynx: 1 time per day, the course - 10 days.
Imunofan in most cases does not cause side effects. Sometimes it is possible to develop allergic reactions.
When imunofan is used, activation of phagocytosis takes place, which can lead to a short-term exacerbation of the foci of chronic inflammation.
In the case of pregnancy complicated by Rhesus-conflict, it is contraindicated to use rectal suppositories and a solution for IM and SC administration. Nasal Spray Imunofan should be used with caution during pregnancy and breastfeeding.
Terms and conditions of storage
The preparation of Imunofan should be stored in a place protected from sunlight, at a temperature of 2 ° C to 10 ° C.
The shelf life of Imunofan is two years.
- Product Code: imunofan
- Availability: In Stock